Was he [David Duchovny] hard to cast?
Chris Carter: He actually came in and read for the part. I didn’t realize how smart he was, because his delivery is so slow. At first I wasn’t impressed. I was looking for a different kind of intelligence. But he read perfectly.
And Gillian Anderson?
Believe me, that was a very difficult, uh, sell to Fox.
This was when “Melrose Place” and “90210″ were big hits for Fox. Were they looking for a Heather Locklear type?
When she came in to read for the part, she was not looking her best. She looked like she had probably been living somewhere in the East Village [in New York] and was dressed kind of funky. She looked nothing like she looks now. But I saw an intensity and an intelligence there that I think would be a part of any person who had gone to medical school, who was young and ambitious. A person who wanted to please her superiors. You knew the chemistry was there with Dave and Gillian. That’s something you pray for, because you can’t manufacture it.
Rolling Stone, February 1997